Tri(Hydroxymethyl) Amino Methane Hydrochloride, ≥99.0%
Product Numbers: K687002
Product name: Tri(Hydroxymethyl) Amino Methane Hydrochloride
English name: Tri(Hydroxymethyl) Amino Methane Hydrochloride
Alias: Tris(hydroxymethyl)aminoethane hydrochloride; Tris(hydroxymethyl)aminomethane hydrochloride; 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL, HYDROCHLORIDE; SPECTRIS(R) HYDROCHLORIDE; SPECTRIS(TM) HYDROCHLORIDE; MOLE-READY- TRIS; 1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride; 3-propanediol,2-amino-2-(hydroxymethyl)-hydrochloride; trizmahydrochloride(trishydrochloride); 2-amino-2-(hydroxymethyl )propane-1,3-diol hydrochloride (1:1); 1,3-propanediol, 2-amino-2-(hydroxymethyl)-, chloride
CAS Number: 1185-53-1
Molecular formula: C4H12ClNO3
Molecular mass: 157.6
EINECS number: 214-684-5
Trometamol hydrochloride properties:
Melting point: 150-152°C
Density: 1.05g/mLat20°C
Storage conditions: StoreatRT.
Solubility: H2O: 4Mat20°C, clear, colorless
Form: crystalline
Color: clearcolorless(40%(w/w)inH2O)solution
PH value: 2.5-4.0 (25℃, 4MinH2O)
PH range of acid-base indicator discoloration: 7.0-9.0
Acidity coefficient (pKa): 8.1(at25℃)
Water solubility: SOLUBLE
λ:260nmAmax:0.12
λ:280nmAChemicalbookmax:0.08
Sensitivity Hygroscopic
BRN3675235
stability:
Stable.Incompatiblewithstrongoxidizingagents,bases,moisture.InChIKey:QKNYBSVHEMOAJP-UHFFFAOYSA-N
CAS database: 1185-53-1 (CASDataBaseReference)
EPA chemical substance information: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1185-53-1)
Introduction: Trometamol hydrochloride is referred to as Tris-HCl. Trometamol hydrochloride buffer (Tris-HCl buffer) is not only widely used as a solvent for nucleic acids and proteins, but also has many important uses
Application: Tris-HCl is used for protein crystal growth under different pH conditions. The low ionic strength of Tris-HCL buffer can be used to form the intermediate fiber of C.elegans lamin. Tris-HCl is also one of the main components of protein running buffer. In addition, Tris-HCL is also an intermediate for the preparation of surfactants, vulcanization accelerators and some drugs. Tris-HCl is also used as a titration standard.
Uses: The pH of all buffers depends on temperature and concentration. For Tris buffer, the pH increases by approximately 0.03 units for every 1°C increase in temperature, and the pH decreases by 0.03-0.05 units for every 10-fold dilution.
For biological buffer
Used as an intermediate in organic synthesis
Security Information:
Dangerous goods mark: Xi
Hazard category code: 36/37/38
Safety Instructions 26-36
WGK Germany :3
RTECS number: TY2900000
F :3
TSCA: Yes
Customs code: 29221980